Hyponatremia Management

Master the intricacies of Hyponatremia Management with this comprehensive guide.

Calculating an appropriate infusion rate to correct hyponatremia:

Infusion rate of Normal Saline:

Wt X 0.5 X  desired change in 24 h in mEq

         _______________________________

                         24  x   0.154

This gives the ml /hr infusion rate of normal saline.

Infusion rate of Hypertonic Saline (use in symptomatic patients with sodium < 120) :

Wt  X 0.5 X desired change in 24 h in mEq

      _______________________________

                          24  X   0.512

This gives the ml/hr infusion rate of hypertonic saline.

1 ml hypertonic saline contains 0.512 mEq of sodium

1 ml normal saline contains 0.154 mEq of sodium

0.5 is the value used in calculations of total body water for women;

for men it is 0.6 and for the elderly it is 0.45

Remember, correction should not exceed 10 mEq in 24 hours, and should not exceed 18 mEq in 48 hours

SIADH

Fluid Restriction to 500- 750 ml / day

Demeclocycline 300 to 600 mg twice daily