BRAIN ABSCESS
Explore effective treatment strategies for brain abscess and its unknown sources of infection. Learn about appropriate antibiotic choices based on patient allergies, including options for those allergic to penicillin.
Unknown Sources of Infection:
Think of Staph Aureus, Streptococcus Pneumoniae, Gram Negative organisms
- If the patient is not allergic to Penicillin:
Vancomycin 1 gm IV q 12 h
Ceftriaxone 2 gm IV g 12h
Metronidazole 500 mg IV q6h
- If the patient is allergic to Penicillin:
Vancomycin 1 gm IV q 12h
Ciprofloxacin 400mg iv q 8h
Metronidazole 500 mg IV q 6h
Associated Sinusitis
Think of Streptococcus Pneumoniae
- If patient is not allergic to Penicillin:
Ceftriaxone
Metronidazole
- If patient is allergic to Penicillin
Vancomycin
Metronidazole
Associated Otitis / Mastoiditis
Think of Streptococcus, Gram negatives, and Anaerobes
- If patient is not allergic to Penicillin
Cefepime 2 gm IV q 8h
Metronidazole
- If patient is allergic to Penicillin
Vancomycin
Aztreonam 2 gm IV q 6h
Metronidazole
If a recent history of Neurosurgical procedure
- Think of Staphylococcus, Gram Negatives
If patient is not allergic to Penicillin
Vancomycin
Cefepime
- If patient is allergic to Penicillin
Vancomycin
Ciprofloxacin
If patient has cyanotic heart disease
Think of Streptococcus Viridans
- If patient is not allergic to penicillin
Ceftriaxone
- If patient is allergic to penicillin
Vancomycin
